Jornal do Sistema Genital e Distúrbios

Role of non-invasive and invasive testing in pregnancy in patients with IVF and PGT

Desislava Markova

More than five million babies are born after Assisted Reproductive Technologies (ARTs). Nowadays ARTs are applied not only for infertile couples but also for couples with monogenic diseases and chromosomal abnormalities. Prenatal genetic testing although still not accepted as a standard procedure for couples requiring IVF has been widely used to end the transmission of genetic diseases. PGT can be applied as Prenatal Genetic Testing for Monogenic diseases (PGT-M), Prenatal Genetic Testing for Aneuploidies (PGT-A) and Prenatal Genetic Testing for Structural Rearrangements (PGT-SR).