Jornal de Virologia e Pesquisa Antiviral

CMV Infection in Atypical Hemolytic Uremic Syndrome

Can Hüzmeli, Hatice Terzi, Ferhan Candan, Ayye KekerKockara, Esin Yildiz  and Mansur Kayatas 

Cytomegalovirus (CMV) is a DNA virus belonging to herpesviridea family. CMV infections are seen at all age groups all through the world. Its seroprevalence is 50% in developed countries and 40- 100% in developing countries. In seropostive cases, the disease develops as result of reactivation following a treatment with immunosuppressive.Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia,thrombocytopenia and renal impairment. Atypical HUS (aHUS) defines non Shigatoxin- HUSand a primary disease due to a disorder in complement alternative pathway regulation.In the present paper, a 60 years old case undergoing plasma exchange for aHUS and found to have CMV pneumonia during follow-up is presented.