Biologia Celular: Pesquisa e Terapia

Harnessing Autophagy for Melanoma Benefit

Marco Corazzari and Penny E Lovat

Harnessing Autophag

Cutaneous melanoma, the most aggressive form of skin cancer, remains one of the most difficult human cancers to treat, with an increasing incidence in developed countries which has risen faster than any other malignancy over the past 40 years.Melanoma occurs when the pigment-producing cells (melanocytes)within the basal epidermis become transformed due to both environmental and genetic risk factors.