Andrologia e Ginecologia: Pesquisa Atual

Molecular Pathology and Therapy of Endometriosis: Revisited

Padmanaban S Suresh, Thejaswini Venkatesh, Thangarasu Rajan and Rie Tsutsumi

Molecular Pathology and Therapy of Endometriosis: Revisited

Endometriosis is among one of the most challenging diseases of the 21st century that affects women in their reproductive age, and its aetiology and pathogenesis remains enigmatic. Unravelling the molecular mechanisms that play a role in the etiopathogenesis of endometriosis has been the subject of intense investigation over the last decade. It is a complex hormone dependent and multifactorial disease involving intricate communications of genetic, immunological, hormonal and environmental factors and the clear understanding of the etiopathogenesis of endometriosis is scarce, as indicated by many studies and recent setbacks in clinical trials.