Jornal de Pesquisa Farmacêutica e Entrega de Medicamentos

Prospect of 19F MRI-Guided Drug Delivery

Y. Bruce Yu and Zhong-Xing Jiang

Prospect of 19F MRI-Guided Drug Delivery

Prescription drugs are tracked all the way from the manufacturerto the patient. But once a drug enters the patient’s body, we lose track of it. We do not know at any given time point, where the drug is, in what form, and how much. However, such information would very useful in optimizing drug therapy for each patient. This information is unlikely to be deducted from a patient’s DAN sequences (e.g.: single nucleotide polymorphisms). Butimage-guided drug delivery has the potential to gather such information.