Biologia Celular: Pesquisa e Terapia

Roles of Mitochondrial DNA Changes on Cancer Initiation and Progression

Masahiro Higuchi

Roles of Mitochondrial DNA Changes on Cancer Initiation and Progression

Mitochondria are essential organelles that generate ATP through oxidative phosphorylation. This process is accomplished by a series of protein complexes and mitochondrial respiratory chains (MRC) encoded by nuclear DNA and mitochondrial DNA (mtDNA).