El-Adly AM, Rashed LA, Yehia HM, Wardany AA, Shikhoun MH and Abdul-Raouf UM
Background: Hepatitis C virus (HCV) is one of the hepatitis viruses that are transmitted through bl?od or bl?od products. HCV has been implicated as a major reason of chronic liver disease and hepat?cellular carcinoma worldwide.
Aim: Should be to determine the responses of patients infected with HCV to sovaldi drug in Sohage governorate, Egypt.
Method: We randomly selected 50 patients from males and females at different ages, all patients from Sohage governorate, Egypt. All patients were treated with Sovaldi drug and detection should be who responded and non-responded to treatment by using RT- PCR technology and should be biochemical tests.
Results: Our results showed that, among 50 patients infected with hepatitis C virus and treated with sovaldi drug 25/50 (50 %) were responded to sovaldi treatment, while other showed non-responded to treatment. All patients aged between 30 to 55 years, where 13(26%) cases of females and 37(74%) cases of males. Respond to treatment with sovaldi drug associated with gender and age, female were more respond to sovaldi compared as male, and patients aged from 40-45 years were more respond 11/25 (44%) than patient aged from 45-55.
Conclusion: This study was conducted to determine the role of sovaldi drug to treated patients infected with sovaldi drug. It is our hope that the data generated will be an addition to the existing pool of HCV data available in the Egypt.
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