Jornal de Ciências Farmacêuticas e Medicamentos Emergentes

An In Vitro Study of Binding of Aceclofenac and Pantoprazole with Bovine Serum Albumin by UV Spectroscopic Method

Sabiha Ferdowsy Koly, Md. Zakir Sultan, Asma Rahman, Shaila Kabir and Mohammad Shah Amran

An In Vitro Study of Binding of Aceclofenac and Pantoprazole with Bovine Serum Albumin by UV Spectroscopic Method

Plasma protein binding is one of the most important pharmacokinetic parameter of drug. The study was designed to determine the binding of Aceclofenac and Pantoprazole to Bovine Serum Albumin. The study was conducted by equilibrium dialysis method followed by measurement using a spectrophotometer at pH 7.4 and 37°C