Jornal de Ciências Farmacêuticas e Medicamentos Emergentes

Pyrrole-Modified Liposomes for Improved Drug Stability and Bioavailability

Miki Shiori

Liposomes have emerged as versatile drug delivery systems due to their biocompatibility, encapsulation efficiency, and ability to carry a wide range of therapeutic agents. However, challenges remain in terms of drug stability and bioavailability. To overcome these limitations, researchers have turned to pyrrole modification of liposomes, a capable strategy that offers enhanced stability and improved drug delivery. Pyrrole, a heterocyclic aromatic compound, possesses unique physicochemical properties that can be harnessed to enhance liposomal drug formulations.