Arquivos de Biotecnologia Médica

The Promise of Bacteriophage Antimicrobial Therapeutics

D. Michael Olive and Joseph O’Connor

With the end of the antibiotic era looming, alternative antimicrobial agents are desperately needed. Lytic bacteriophage specific for a variety of bacteria have been used for almost 100 years to successfully treat serious infections. Here we make the case for pursuing formal regulatory approvals for the use of bacteriophage as therapeutic antimicrobial agents.