Jornal de Técnicas Imunológicas e Doenças Infecciosas

Standardization of a Multiplex Magnetic Bead-based for Simultaneous Detection of IgG to Plasmodium Antigens

Perraut R, Varela M-L, Mbengue B, Guillotte M, Mercereau-P uijalon O and Vigan-Womas I

Standardization of a Multiplex Magnetic Bead-based for Simultaneous Detection of IgG to Plasmodium Antigens

Multiplex assays are currently used to facilitate the evaluation of antibody (Ab) responses to multiple Plasmodium falciparum antigens from large field-based epidemiological studies. The present study aimed at (i) optimizing parameters of a novel cost-effective, compact and reliable magnetic bead-based multiplex immunoassay (MBA) carried out with the MAGPIX®-Luminex system and (ii) comparing the results with those obtained using standard ELISA technology.